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With the

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advancement of local drug delivery systems, restorative dentists, periodontists, and their patients have new alternatives for the treatment of periodontal disease.

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In some patients, periodontal disease appears in a generalized form, but more often it appears in localized areas. Therapy of pneumococcal infections is made difficult by the

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emergence and spread of bacterial resistance to Penicillin VK (V-Cillin generic imitrex injections K) and other beta-lactams as well as to a number of antimicrobials such as macrolides, chloramphenicol, tetracyclines and sulfonamides. This epidemiological situation is a cause for concern

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world-wide, but it primarily affects some European countries, North America, prescription drugs pregnancy South Africa and the Far East. Pneumoniae

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as a cause of nosocomial infections of respiratory tract,

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bloodstream and central nervous system is more and more recognized, primarily in high-risk patients with depression of their immune function. Because periodontitis is a bacterial infection

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with known pathogenic microorganisms, the local delivery of antimicrobial agents has been considered to be a possible solution for treating and controlling localized forms of periodontal disease.

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Furthermore, after treatment with scaling and root

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planing in generalized cases, the disease is often reduced to a few local areas in the patient's mouth. Treatment in the era of Penicillin VK (V-Cillin K)-resistant strains.Streptococcus pneumoniae is a well-known agent of community-acquired infections such as sinusitis, otitis media, pneumonia, bacterial meningitis, bacteremia and acute exacerbations

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of chronic bronchitis. In both in vivo and in vitro studies, drugs of the classes of fluoroquinolones (Levofloxacin ( Levaquin ),

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moxifloxacin, gatifloxacin), streptogramins (quinupristin/dalfopristin) and oxazolidinones (linezolid) have shown good microbiologic and clinical efficacy against Penicillin VK (V-Cillin K)-resistant pneumococci. Streptococcus pneumoniae as an agent of nosocomial infection.

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Local chemotherapeutic agents offer an additional mode of therapy and should be used on a case-by-case basis, not necessarily as an initial treatment. Three local chemotherapeutic agents are revie

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in this paper. In this era of world-wide spread of Penicillin VK (V-Cillin K)-resistant pneumococci, use of polysaccaride or conjugated vaccines is highly recommended.. The use of chemotherapeutic agents in localized periodontal pockets.Gingival diseases are the most widely dispersed

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diseases in the United States. However, a beta-lactam agent can also be a valid choice in the presence of potentially lethal infections such as pneumonia or in the case of Penicillin VK (V-Cillin K) intermediately resistant isolates. Tetracycline fiber, doxycycline

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(Doryx)gel, and chlorhexidine chip.

The main consequence on therapeutic grounds is that in severe infections such as bacterial meningitis, the addition of vancomycin to a third-generation cephalosporin is advisable while awaiting laboratory test results, even in areas with low prevalence of Penicillin VK (V-Cillin K)-resistant pneumococci. In recent years, new alternative molecules have been introduced into clinical practice for therapy of infections caused by Penicillin VK (V-Cillin K)-resistant pneumococci.